A Weaning Reaction to Microbiota Is Required for Resistance to Immunopathologies in the Adult
6/13/2019
Al Nabhani Z, Dulauroy S, Marques R, Cousu C, Al Bounny S, Déjardin F, Sparwasser T, Bérard M, Cerf-Bensussan N, Eberl G.
Here, Al Nabhani et al, show an essential step in the induction of intestinal tolerance is a marked immune response at weaning. Disrupting this microbial-driven response results in susceptibility to immunopathologies later in life.